Will “DeSci” be the next big trend after DePIN?

What is DeSci?

DeSci, or Decentralized Science, is a movement using blockchain and decentralized technologies to revolutionize scientific research. It aims to fix key problems like limited funding, restricted access, reproducibility challenges, and institutional gatekeeping.

Decentralized Science (DeSci) leverages blockchain technology to revolutionize scientific research funding and collaboration. Instead of relying on large institutions or complex funding processes, DeSci allows scientists to connect directly with the community or investors, making it easier to secure funding through tools like Tokens, NFTs, and DAOs.

This provides a quick way for scientists to find funding or protect their ideas. For the community, DeSci offers the opportunity to participate in and benefit from future scientific innovations.

At an event organized by Binance Labs called DeSci Day, both CZ and Vitalik Buterin engaged in discussions with leading projects in the DeSci field, such as BIO Protocol, VitaDAO, and HairDAO. CZ remarked, “Crypto now has a solid foundation to be applied in the field of science.”

This trend is gaining attention thanks to Binance Labs and the presence of CZ. However, he mentioned this sector as early as 2023 on his personal X account, highlighting its significant potential. He said, “I have been exploring biotechnology and thinking about how to use crypto to accelerate funding for research in this field.”

In October 2022, Coinbase CEO Brian Armstrong also expressed bullish sentiments about this trend, stating, “I am passionate about advancing science and technology to address some of the world’s biggest challenges. To continue this mission, I plan to sell about 2% of my Coinbase shares next year to fund scientific research.”

Although this trend is in its early stages, researching and identifying quality projects early on can give you an investment advantage.

DeSci’s mission is to create a transparent, efficient, and equitable system for conducting and sharing scientific research. By aligning incentives and breaking down barriers, it empowers researchers and communities to innovate together.

Top DeSci projects to watch

BIO Protocol

BIO Protocol is at the forefront of the Decentralized Science (DeSci) movement, leveraging BioDAOs (blockchain-based Decentralized Autonomous Organizations) to revolutionize biotech research.

By creating a new financial layer for scientific projects, the BIO Protocol connects researchers, healthcare enthusiasts, and investors to collaborate on groundbreaking innovations. BioDAO members receive profits when successful projects are commercialized, ensuring that the community shares in the rewards of scientific advancements.

Key Highlights

• Funding Success: Raised $33.06 million via the Genesis Complete event.
• Endorsement by Binance Labs: A significant vote of confidence from one of the leading venture funds.
• DeSci Thought Leadership: BIO Protocol has engaged in high-level discussions with figures like CZ and Vitalik Buterin on blockchain’s role in transforming scientific research.

BIO Protocol’s unique approach to funding and collaboration positions it as a leading player in the DeSci ecosystem.

Notable Specialized DAOs

• VitaDAO: With over $5 million raised, VitaDAO supports research into aging and human lifespan extension.
• HairDAO: Focuses on developing new treatments for hair loss, helping millions affected by this issue.
• CerebrumDAO: Raised $1.5 million to improve brain health, with a focus on mitochondrial disorders and neurodegenerative diseases.
• ValleyDAO: Over $2 million raised, partnering with Imperial College London to accelerate synthetic biology innovations.
• AthenaDAO: A rare DAO focused on addressing women’s health challenges.
• CryoDAO: Specializes in cryotechnology to enhance the preservation of cells, tissues, and biological compounds.
• PsyDAO: Dedicated to advancing mental health treatments through pharmaceutical research.

These DAOs provide targeted investment opportunities in biotech areas with high potential for growth and impact.

Molecule Protocol

Molecule connects researchers with funding and resources by offering a platform that helps communities manage and tokenize intellectual property (IP) in the form of patents, research papers, and databases. By turning research IP into tradable NFTs, Molecule ensures transparency and fairness in sharing scientific advancements.

With $14 million raised from investors like Backed and Shine Capital, Molecule’s model democratizes funding while creating new opportunities for ownership and collaboration in biotech.

ResearchHub

ResearchHub is transforming the way scientific knowledge is shared by using blockchain technology and its token, RSC. It incentivizes researchers to share findings, collaborate on projects, and engage in discussions, accelerating the pace of scientific discovery.

As a decentralized “GitHub for science,” ResearchHub fosters transparency and openness in the research community, rewarding contributors with financial incentives. The platform has seen RSC’s value increase nearly 500%, and with its future potential to monetize research data, it’s poised for significant growth.

These DeSci platforms are shaping the future of scientific research and funding, creating new avenues for investors, researchers, and communities to engage with groundbreaking innovations.

Why is DeSci trending?

DeSci is transforming scientific research by leveraging blockchain technology to remove barriers like slow funding, limited access, and institutional gatekeeping. It creates a more open, transparent, and equitable system for researchers and the public.

With smart contracts and decentralized platforms, DeSci ensures tamper-proof data, secure intellectual property tokenization, and global collaboration. It allows researchers to raise funds directly through crowdfunding or DAOs, bypassing traditional funding agencies and enabling faster, more inclusive innovation.

DeSci also integrates with Web3, where tokenized research, decentralized publishing, and community governance are becoming the norm. By ensuring transparency and accountability, DeSci helps rebuild trust in science, addressing issues like plagiarism and reproducibility.

Real-world projects like VitaDAO and LabDAO are showing the power of DeSci to democratize science, creating a faster, fairer, and more transparent research ecosystem.

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